Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 6/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 6/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6993006 | 0.99 | NPY1R (0.54) | NPY1RSMN1; SMN2KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL7090266 | 0.94 | NPY1R (0.54) | NPY1RSMN1; SMN2KCNJ6KCNJ3KCNJ5 | |
| Hydrochloric Acid SCHEMBL6990784 | 0.93 | NPY1R (0.53) | NPY1RSMN1; SMN2KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL7051912 | 0.90 | NPY1R (0.52) | NPY1RSMN1; SMN2MAPTPOLBNPC1 | |
| SCHEMBL7051909 | 0.90 | NPY1R (0.52) | NPY1RSMN1; SMN2MAPTPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL6990944 | 0.87 | NPY1R (0.55) | NPY1RMAPTPOLBNPC1KMT2A | |
| SCHEMBL7049983 | 0.87 | NPY1R (0.53) | NPY1RSMN1; SMN2MAPTPOLBNPC1 | |
| SCHEMBL7049987 | 0.87 | NPY1R (0.53) | NPY1RSMN1; SMN2MAPTPOLBNPC1 | |
| SCHEMBL7091275 | 0.86 | HTR1A (0.54) | NPY1RSMN1; SMN2MAPTNPC1KMT2A | |
| Hydrochloric Acid SCHEMBL6990799 | 0.85 | HTR1A (0.54) | NPY1RSMN1; SMN2MAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | claimed |
| EP-0915859-B1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0915859-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003492-A1 | CERTAIN SUBSTITUTED BENZYLAMINE DERIVATIVES; A NEW CLASS OF NEUROPEPTIDE Y1 SPECIFIC LIGANDS | NEUROGEN CORPORATION (US) | 1998-01-29 | — | — | WO | disclosed |