Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430696 | 0.91 | PTGS2 (0.42) | PTGS2PTGS1PGRBRAF | |
| SCHEMBL6994340 | 0.90 | PTGS2 (0.35) | PTGS2PTGS1PGR | |
| SCHEMBL6994777 | 0.89 | PGR (0.40) | PTGS2PTGS1PGR | |
| SCHEMBL6991869 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1PGR | |
| SCHEMBL6996081 | 0.89 | PTGS2 (0.44) | PTGS2PTGS1PGR | |
| SCHEMBL7003571 | 0.89 | PTGS2 (0.33) | PTGS2PTGS1PGRBRAF | |
| SCHEMBL6992989 | 0.88 | PTGS2 (0.32) | PTGS2PTGS1PGR | |
| SCHEMBL7001798 | 0.87 | PTGS2 (0.43) | PTGS2PTGS1PGR | |
| SCHEMBL6995643 | 0.87 | PTGS2 (0.37) | PTGS2PTGS1PGRBRAF | |
| SCHEMBL6994703 | 0.87 | PTGES (0.34) | PTGS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | claimed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | claimed |
| EP-1109799-B1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-12-17 | — | — | EP | disclosed |
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |