Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | TACR1 | P25103 | 5/20 | 0.34 |
| ▸ | TACR2 | P21452 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996937 | 0.92 | TP53 (0.40) | HPGDGLP1RGCGRSLC6A3 | |
| SCHEMBL6990244 | 0.91 | TP53 (0.38) | MEN1POLBKMT2AGCGRELOVL6 | |
| SCHEMBL6992764 | 0.91 | HPGD (0.39) | AKT1HPGDMEN1KMT2AGLP1R | |
| SCHEMBL7144829 | 0.91 | TRPV1 (0.42) | CCR5GCGR | |
| SCHEMBL6988551 | 0.89 | TP53 (0.35) | TACR1CCR5MEN1POLBKMT2A | |
| SCHEMBL6997966 | 0.89 | MEN1 (0.34) | MDM2MEN1POLBKMT2AGLP1R | |
| SCHEMBL6986470 | 0.88 | HPGD (0.38) | HPGDMEN1POLBKMT2AGLP1R | |
| SCHEMBL6994214 | 0.87 | MEN1 (0.36) | TACR1MEN1POLBKMT2ADPP4 | |
| SCHEMBL6989614 | 0.83 | TP53 (0.47) | MEN1POLBKMT2AGCGR | |
| SCHEMBL6991739 | 0.82 | TRPV1 (0.38) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358176-A2 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | Amura Therapeutics Limited (GB) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002057246-A2 | INHIBITORS OF CRUZIPAIN AND OTHER CYSTEINE PROTEASES | AMURA THERAPEUTICS LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |