Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989336 | 0.96 | KMT2A (0.42) | KMT2AMEN1PDE10AMAPTTSHR | |
| SCHEMBL38663373 | 0.81 | PDE10A (0.49) | KMT2AMEN1PDE10AMAPTTSHR | |
| SCHEMBL3911544 | 0.81 | POLB (0.41) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3898772 | 0.79 | ACHE (0.32) | — | |
| SCHEMBL3904667 | 0.79 | ACHE (0.32) | KMT2AALDH1A1NPSR1 | |
| SCHEMBL6177768 | 0.76 | KDM4E (0.30) | KDM4EALDH1A1HPGD | |
| SCHEMBL38661829 | 0.76 | MEN1 (0.49) | KMT2AMEN1PDE10AMAPTTSHR | |
| SCHEMBL1054774 | 0.76 | MEN1 (0.49) | KMT2AMEN1PDE10AMAPTTSHR | |
| SCHEMBL7047666 | 0.76 | PDE10A (0.43) | KMT2AMEN1PDE10AMAPTTSHR | |
| SCHEMBL28129469 | 0.73 | MEN1 (0.60) | KMT2AMEN1PDE10AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656005-B1 | BIOTINYLATED CHEMILUMINESCENT LABEL, CONJUGATES, ASSAYS, ASSAY KITS | NICHOLS INST DIAGNOSTICS (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-0656005-A4 | BIOTINYLATED CHEMILUMINESCENT LABELS, CONJUGATES, ASSAYS, ASSAY KITS. | NICHOLS INST DIAGNOSTICS (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0656005-A1 | BIOTINYLATED CHEMILUMINESCENT LABELS, CONJUGATES, ASSAYS, ASSAY KITS | NICHOLS INSTITUTE DIAGNOSTICS (US) | 1995-06-07 | — | — | EP | disclosed |
| US-5395938-A | Streptavidin and/or avindin conjugates | NICHOLS INSTITUTE DIAGNOSTICS (US) | 1995-03-07 | — | — | US | disclosed |
| WO-1994004538-A1 | BIOTINYLATED CHEMILUMINESCENT LABELS, CONJUGATES, ASSAYS, ASSAY KITS | NICHOLS INSTITUTE DIAGNOSTICS (US) | 1994-03-03 | — | — | WO | disclosed |
| US-5284952-A | Sulfonyl substituted chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |