Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992915 | 0.81 | KMT2A (0.39) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3907870 | 0.80 | PLK1 (0.34) | ALDH1A1MAPTKDM4EFABP4 | |
| SCHEMBL3896152 | 0.80 | PLA2G2A (0.34) | ALDH1A1KDM4EFABP4 | |
| SCHEMBL6989336 | 0.76 | KMT2A (0.42) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28129469 | 0.74 | MEN1 (0.60) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7047504 | 0.74 | KMT2A (0.47) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9425726 | 0.73 | MAPT (0.39) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3899652 | 0.71 | ACLY (0.36) | POLBALDH1A1MAPTDHODHFABP4 | |
| SCHEMBL10516077 | 0.70 | NPC1 (0.50) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29785793 | 0.69 | TRPV4 (0.55) | POLBALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916658-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-0322926-B2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0322926-B1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | NICHOLS INST DIAGNOSTICS (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0916658-A1 | Assays utilizing improved chemiluminescent esters, thioesters and amides | Nichols Institute Diagnostics (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5284952-A | Sulfonyl substituted chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0322926-A2 | Assays utilizing improved chemiluminescent esters, thioesters and amides | LONDON DIAGNOSTICS, INC. (US) | 1989-07-05 | — | — | EP | disclosed |