SCHEMBL699293

SCHEMBL699293

Oc1ccc(C2(c3ccc(O)cc3C3CCCCC3)CCCCC2)c(C2CCCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 4/20 0.43
OPRM1 P35372 4/20 0.40
OPRD1 P41143 4/20 0.39
OPRK1 P41145 3/20 0.39
OPRL1 P41146 1/20 0.39
HSP90AA1 P07900 1/20 0.39
SLC22A1 O15245 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
NUDT1 P36639 1/20 0.36
BACE1 P56817 1/20 0.36
HSP90AB1 P08238 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
ADRA2A P08913 1/20 0.35
SLC6A4 P31645 1/20 0.35
SCN1A P35498 1/20 0.35
GRIN1 Q05586 1/20 0.35
KCNH2 Q12809 1/20 0.35
GRIN2A Q12879 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578994 0.80 HSP90AA1 (0.44) ESR1ESR2OPRM1OPRD1OPRK1
SCHEMBL29108770 0.80 HSP90AA1 (0.44) ESR1ESR2OPRM1OPRD1OPRK1
SCHEMBL10438722 0.78 DYRK1A (0.54) ESR1ESR2HSP90AA1NUDT1BACE1
SCHEMBL17699117 0.76 CHRNB2 (0.55) ESR1ESR2HSP90AA1NUDT1BACE1
SCHEMBL25280688 0.75 PDK2 (0.43) ESR1ESR2
SCHEMBL10941119 0.75 ESR2 (0.59) ESR1ESR2OPRM1OPRD1OPRK1
SCHEMBL69755 0.74 NUDT1 (0.57) ESR1ESR2HSP90AA1NUDT1BACE1
SCHEMBL9540995 0.74 DYRK1A (0.44) ESR1ESR2HSP90AA1NUDT1BACE1
SCHEMBL278620 0.73 ESR1 (0.56) ESR1ESR2HSP90AA1NUDT1BACE1
SCHEMBL9008331 0.73 ESR1 (0.56) ESR1ESR2HSP90AA1NUDT1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223985-B1 ORDINARY-TEMPERATURE-PHOSPHORESCENT ORGANIC MATERIAL, REVERSIBLY THERMOSENSITIVE RECORDING MATERIAL, REVERSIBLY THERMOSENSITIVE RECORDING MEDIUM, AND METHOD OF RECORDING IN REVERSIBLY THERMOSENSITIVE RECORDING MEDIUM UNIV TOKYO NAT UNIV CORP (JP) 2013-07-31 EP disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
EP-2424018-A1 Polyarylene block copolymer having sulfonic acid group and use thereof JSR Corporation (JP) 2012-02-29 EP disclosed