SCHEMBL9540995

SCHEMBL9540995

Oc1ccc(-c2cc(-c3ccc(O)cc3C3CCCCC3)cc(-c3ccc(O)cc3C3CCCCC3)c2)c(C2CCCCC2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.44
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
FEN1 P39748 3/20 0.38
NUDT1 P36639 1/20 0.38
BACE1 P56817 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
ALOX5AP P20292 2/20 0.38
PTPN5 P54829 2/20 0.37
PTPN2 P17706 1/20 0.37
PTGDR2 Q9Y5Y4 2/20 0.37
PDK2 Q15119 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
PRKCI P41743 1/20 0.37
PTGDR Q13258 1/20 0.37
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10407361 0.91 ESR1 (0.48) DYRK1AESR1ESR2FEN1NUDT1
SCHEMBL10438722 0.90 DYRK1A (0.54) DYRK1AESR1ESR2FEN1NUDT1
SCHEMBL21817076 0.82 HSD17B1 (0.45) ESR1ESR2FEN1ALOX5APPTGDR2
SCHEMBL29402603 0.82 HSD17B1 (0.45) ESR1ESR2FEN1ALOX5APPTGDR2
SCHEMBL17699117 0.80 CHRNB2 (0.55) DYRK1AESR1ESR2NUDT1BACE1
SCHEMBL69755 0.79 NUDT1 (0.57) DYRK1AESR1ESR2NUDT1BACE1
SCHEMBL28101898 0.78 PTGDR2 (0.45) ESR1ESR2FEN1ALOX5APPTGDR2
SCHEMBL28931577 0.76 ESR1 (0.44) ESR1ESR2NUDT1BACE1HSP90AA1
Bromide SCHEMBL28390505 0.76 PTGS2 (0.44) FEN1HSP90AA1ALOX5APPTPN5PTPN2
SCHEMBL10899805 0.76 NUDT1 (0.54) DYRK1AESR1ESR2NUDT1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993014140-A1 EPOXIDATION PRODUCTS OF 1,3,5-TRIS(4'-HYDROXYPHENYL)BENZENES____ HOECHST CELANESE CORPORATION (US) 1993-07-22 WO disclosed