Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046499 | 0.87 | MMP12 (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL2105843 | 0.77 | MMP12 (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL225931 | 0.74 | MMP12 (0.73) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL1266231 | 0.73 | MMP12 (0.62) | MMP12MAPTKDM4EBLMP2RY14 | |
| SCHEMBL31465271 | 0.73 | MMP12 (0.62) | MMP12MAPTKDM4EBLMP2RY14 | |
| SCHEMBL23366512 | 0.72 | MMP12 (0.41) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL3162533 | 0.71 | MMP12 (0.50) | MMP12MAPTKDM4EALDH1A1 | |
| SCHEMBL6364797 | 0.71 | MMP12 (0.46) | MMP12MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL31411494 | 0.70 | PARP1 (0.60) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL1799379 | 0.70 | QPCTL (0.45) | MMP12MAPTKDM4EALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844998-B1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | disclosed |
| US-20030027842-A1 | Halogenobenzimidazoles | ASSMANN LUTZ (DE) | 2003-02-06 | — | — | US | disclosed |
| US-6387939-B1 | PLANT SAFENING AGNETS; FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-14 | — | — | US | disclosed |
| US-6268508-B1 | FOR CROP PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
| US-6160001-A | Halobenzimidazoles and their use as microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-6127547-A | FOR CROP PROTECTION; SUCH AS 2-BROMO-6,6-DIFLUORO(1,3)DIOXOLO(4,5-F)BENZIMIDAZOLE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6020354-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-01 | — | — | US | disclosed |
| EP-0844998-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1997006171-A1 | HALOBENZIMIDAZOLES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027842-A1 | Halogenobenzimidazoles | MSR1, MRPS23, CBR1 | MMP12 1483/4885MAPT 4367/4885KDM4E 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.