Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.41 |
| ▸ | ADH1A | P07327 | 3/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356542 | 0.79 | — | — | |
| SCHEMBL7669607 | 0.77 | ADH1B (0.73) | ADH1BADH1AADH1CADH7 | |
| SCHEMBL873604 | 0.77 | — | — | |
| SCHEMBL7673181 | 0.72 | ADH1B (0.68) | ADH1BADH1AADH1CADH7 | |
| Propionaldehyde SCHEMBL1412137 | 0.72 | ALDH1A1 (0.53) | — | |
| SCHEMBL8808939 | 0.72 | ADH1B (0.36) | ADH1BADH1AADH1C | |
| Malonaldehyde SCHEMBL8113991 | 0.72 | ALDH1A1 (0.30) | — | |
| Butanal SCHEMBL6247082 | 0.71 | ALDH1A1 (0.60) | ADH1BADH1AADH7 | |
| SCHEMBL2075451 | 0.70 | — | — | |
| SCHEMBL483681 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1015446-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | Aventis Pharmaceuticals Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1998034933-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-13 | — | — | WO | disclosed |