Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993137 | 1.00 | MEN1 (0.40) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL6990958 | 0.88 | ODC1 (0.40) | — | |
| SCHEMBL6990960 | 0.88 | ODC1 (0.40) | — | |
| SCHEMBL6992519 | 0.86 | NOS1 (0.31) | — | |
| SCHEMBL6992523 | 0.86 | NOS1 (0.31) | — | |
| SCHEMBL6994163 | 0.86 | NOS1 (0.31) | — | |
| SCHEMBL6653415 | 0.84 | GGT1 (0.35) | ARG1ARG2 | |
| SCHEMBL6130672 | 0.84 | GGT1 (0.35) | ARG1ARG2 | |
| SCHEMBL6130511 | 0.84 | GGT1 (0.35) | ARG1ARG2 | |
| SCHEMBL6992291 | 0.84 | GGT1 (0.35) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317421-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| WO-2002022562-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |