Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.34 |
| ▸ | CA1 | P00915 | 13/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 7/20 | 0.32 |
| ▸ | CA9 | Q16790 | 7/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HAT1 | O14929 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113338 | 0.93 | — | — | |
| SCHEMBL6994308 | 0.90 | CYP3A4 (0.32) | — | |
| SCHEMBL6993302 | 0.90 | ALOX5 (0.32) | — | |
| SCHEMBL7002397 | 0.89 | ALOX5 (0.31) | — | |
| SCHEMBL7002041 | 0.89 | CYP3A4 (0.39) | KDM4E | |
| SCHEMBL8137237 | 0.89 | ALOX5 (0.35) | — | |
| SCHEMBL7000917 | 0.88 | AR (0.32) | KMT2A | |
| SCHEMBL7001863 | 0.87 | ALDH1A1 (0.33) | MEN1KMT2AKDM4E | |
| SCHEMBL6998556 | 0.87 | — | — | |
| SCHEMBL7001710 | 0.85 | FFAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | disclosed |