Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640549 | 0.83 | POLB (0.57) | ROCK2POLBLMNAUSP2CYP1A2 | |
| SCHEMBL6997742 | 0.77 | RAB9A (0.49) | ROCK2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL13434069 | 0.71 | HPGD (0.69) | POLBHDAC1HPGDHTTALDH1A1 | |
| SCHEMBL6995500 | 0.71 | ALDH1A1 (0.50) | ROCK2POLBLMNAUSP2CYP1A2 | |
| SCHEMBL6994625 | 0.71 | POLB (0.53) | ROCK2POLBLMNAUSP2CYP1A2 | |
| SCHEMBL1568381 | 0.71 | HDAC1 (0.72) | ROCK2POLBUSP2CYP1A2CYP3A4 | |
| SCHEMBL8122573 | 0.70 | POLB (0.63) | POLBHDAC1HPGDHTTALDH1A1 | |
| SCHEMBL13779327 | 0.68 | POLB (0.67) | ROCK2POLBUSP2HDAC1HPGD | |
| SCHEMBL21722443 | 0.67 | POLB (1.00) | POLBLMNACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17783473 | 0.67 | ROCK2 (1.00) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |