Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 7/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991988 | 0.88 | AVPR1A (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6995228 | 0.87 | AVPR2 (0.51) | AVPR2AVPR1AAVPR1BMAP3K7 | |
| SCHEMBL6988080 | 0.86 | AVPR2 (0.61) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6987523 | 0.86 | AVPR2 (0.56) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6989777 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6996850 | 0.84 | LMNA (0.51) | AVPR2AVPR1AAVPR1BKMT2A | |
| SCHEMBL6989537 | 0.83 | AVPR1A (0.55) | AVPR2AVPR1AAVPR1BALDH1A1KMT2A | |
| SCHEMBL8796584 | 0.80 | AVPR1A (0.61) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL6993361 | 0.78 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1BKMT2A | |
| SCHEMBL8796741 | 0.77 | AVPR1A (0.73) | AVPR2AVPR1AAVPR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811008-B1 | BICYCLIC BENZAZEPINE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2003-10-01 | — | — | EP | disclosed |