Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2142147 | 0.91 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL3793157 | 0.88 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL3835073 | 0.86 | CSNK2A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL17171674 | 0.86 | GRM1 (0.56) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL69934 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL238021 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL30932083 | 0.82 | GABRP (0.48) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL29350418 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL19331350 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 | |
| SCHEMBL70135 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. | 2020-07-02 | — | — | US | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| US-9889412-B2 | Composite gas separation membrane, gas separation module, gas separation apparatus and gas separation method | FUJIFILM CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9889412-B2 | Composite gas separation membrane, gas separation module, gas separation apparatus and gas separation method | FUJIFILM CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20160184779-A1 | COMPOSITE GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS AND GAS SEPARATION METHOD | FUJIFILM CORPORATION (JP) | 2016-06-30 | — | — | US | disclosed |
| US-20160066578-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | Akeso Biomedical, Inc. | 2016-03-10 | — | — | US | disclosed |
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| WO-2010095678-A1 | FLUORINATED DICARBOXYLIC ACID DERIVATIVE AND POLYMER OBTAINED THEREFROM | セントラル硝子株式会社 (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010047982-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010036613-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | KDM4E 253/4885ALDH1A1 3942/4885HPGD 3204/4885 |
| US-20160066578-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | TYR, TH, DDC | KDM4E 1578/4885ALDH1A1 1361/4885HPGD 830/4885 |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | MCCC2, AFF2, F13A1 | KDM4E 2650/4885ALDH1A1 181/4885HPGD 4150/4885 |
| US-20200207716-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | MTOR, RICTOR, RPTOR | KDM4E 253/4885ALDH1A1 3942/4885HPGD 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.