Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113009 | 0.85 | TDP1 (0.42) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL4157946 | 0.85 | ALDH1A1 (0.52) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL12003617 | 0.82 | ALDH1A1 (0.39) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL699377 | 0.81 | ALDH1A1 (0.38) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL698113 | 0.80 | ALDH1A1 (0.37) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL696900 | 0.79 | ALDH1A1 (0.41) | TDP1CYP3A4ALDH1A1TSHRMAPT | |
| SCHEMBL11808310 | 0.73 | CYP3A4 (0.54) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL273206 | 0.73 | CYP3A4 (0.54) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL6371600 | 0.71 | CYP3A4 (0.52) | TDP1CYP3A4ALDH1A1TSHRS100B | |
| SCHEMBL12775090 | 0.69 | TDP1 (0.52) | TDP1CYP3A4ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661886-B1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS AGRO INC (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-9101135-B2 | Agricultural/horticultural insecticide and method for using the same | MITSUI CHEMICALS, INC. (JP) | 2015-08-11 | — | — | US | disclosed |
| US-9089133-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20140303377-A1 | AGRICULTURAL/HORTICULTURAL INSECTICIDE AND METHOD FOR USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2014-10-09 | — | — | US | disclosed |
| US-8816128-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20130066114-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20120220802-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-8158814-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2423188-A1 | Agricultural/Horticultural Insecticide and Method for Using the Same | MITSUI CHEMICALS AGRO, INC. (JP) | 2012-02-29 | — | — | EP | disclosed |
| EP-1661886-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303377-A1 | AGRICULTURAL/HORTICULTURAL INSECTICIDE AND METHOD FOR USING THE SAME | CBR3, ATL3, CNPY2 | TDP1 2795/4885CYP3A4 166/4885ALDH1A1 1956/4885 |
| US-20120220802-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | CYP1A2, CYP2C9, CYP3A7 | TDP1 2554/4885CYP3A4 17/4885ALDH1A1 145/4885 |
| US-20130066114-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | CYP2C8, CYP4F8, CYP3A7 | TDP1 2440/4885CYP3A4 16/4885ALDH1A1 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.