Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994052 | 0.87 | ABCB11 (0.52) | ABCB11CCR2 | |
| SCHEMBL6596985 | 0.83 | ABCB11 (0.78) | ABCB11CCR2 | |
| SCHEMBL6598022 | 0.81 | ABCB11 (1.00) | ABCB11CCR2 | |
| SCHEMBL6780988 | 0.81 | ABCB11 (0.75) | ABCB11CCR2 | |
| SCHEMBL6303492 | 0.79 | CCR2 (0.74) | ABCB11CCR2 | |
| SCHEMBL6308083 | 0.78 | CCR2 (0.81) | ABCB11CCR2 | |
| SCHEMBL6300905 | 0.76 | CCR2 (1.00) | ABCB11CCR2 | |
| SCHEMBL7682986 | 0.75 | ABCB11 (0.71) | ABCB11CCR2 | |
| SCHEMBL7084558 | 0.75 | CCR2 (0.73) | ABCB11CCR2 | |
| SCHEMBL6598736 | 0.73 | CCR2 (0.73) | ABCB11CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150953-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| US-6613760-B1 | Compounds such as N-(3,4-Dichlorobenzyl)-2-ethoxycarbonyl-indole-4-carboxylic acid, used as inhibitors of monocyte chemoattractant proteins (MCP-1) and RANTES induced chemotaxis; antiinflammatory agents | ASTRAZENECA AB (SE) | 2003-09-02 | — | — | US | disclosed |