SCHEMBL699415

SCHEMBL699415

COC(=O)c1cccc(C)c1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
TSHR P16473 1/20 0.52
NR4A2 P43354 1/20 0.51
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 3/20 0.50
CFTR P13569 1/20 0.50
KDM4E B2RXH2 6/20 0.49
HPGD P15428 2/20 0.49
POLB P06746 2/20 0.48
ATM Q13315 1/20 0.48
GAA P10253 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
MYC P01106 1/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 4/20 0.46
ALOX15 P16050 2/20 0.46
NPC1 O15118 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18537273 0.96 TSHR (0.53) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL3511611 0.90 TSHR (0.57) LMNATSHRALDH1A1HSD17B10CFTR
SCHEMBL12313575 0.84 CXCR5 (0.52) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL16959103 0.84 TSHR (0.46) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL9726590 0.83 KDM4E (0.52) LMNAALDH1A1HSD17B10KDM4EHPGD
SCHEMBL11678098 0.83 TSHR (0.63) LMNATSHRALDH1A1HSD17B10KDM4E
SCHEMBL12569625 0.83 NR4A2 (0.44) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL7197691 0.83 ALDH1A1 (0.49) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL4955520 0.83 TDP1 (0.54) LMNATSHRNR4A2ALDH1A1HSD17B10
SCHEMBL23092927 0.82 LMNA (0.50) LMNATSHRALDH1A1HSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP claimed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO claimed
CN-122037370-A Conductive polypropylene composition, and preparation method and application thereof 中国石油化工股份有限公司 2026-05-15 CN disclosed
US-20260108482-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS INC (US) 2026-04-23 US disclosed
CN-115380030-B N-heteroarylalkyl-2- (heterocyclyl and heterocyclylmethyl) acetamide derivatives as SSTR4 agonists 武田药品工业株式会社 2025-05-16 CN disclosed
CN-113939288-B Modulators of MAS-related G protein receptor X4 and related products and methods 伊赛恩特制药公司 2025-04-25 CN disclosed
CN-119614722-A Screening method of novel dicyclo borate beta-lactamase inhibitor 南京灿辰微生物科技有限公司 2025-03-14 CN disclosed
US-20240300907-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS INCYTE CORPORATION 2024-09-12 US disclosed
CN-117924555-A Catalyst component, catalyst system, application of catalyst system and olefin polymerization method 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-117924556-A Spherical magnesium halide adduct and preparation method and application thereof 中国石油化工股份有限公司 2024-04-26 CN disclosed
US-6406297-B1 USED FOR DETECTING AND QUANTIFYING CHEMICAL, BIOCHEMICAL AND BIOLOGICAL SUBSTANCES AS ANALYTES IN RESEARCH AND DIAGNOSTIC MIXTURES. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-06-18 US disclosed
US-6127356-A MODULATING INTRA- OR EXTRACELLULAR LEVELS OF OXIDANTS SUCH AS SUPEROXIDE RADICALS, HYDROGEN PEROXIDE AND PEROXYNITRITES BY USING LOW MOLECULAR WEIGHT MIMETICS OF SUPEROXIDE DISMUTASE, CATALASE OR PEROXIDASE DUKE UNIVERSITY (US) 2000-10-03 US disclosed
EP-0831891-A4 OXIDANT SCAVENGERS UNIV DUKE (US) 1999-02-03 EP disclosed
EP-0831891-A1 OXIDANT SCAVENGERS DUKE UNIVERSITY (US) 1998-04-01 EP disclosed
WO-1996040223-A1 OXIDANT SCAVENGERS DUKE UNIVERSITY (US) 1996-12-19 WO disclosed
US-5234942-A Treating allergic pulmonary disorders, asthma ICI AMERICAS INC. (US) 1993-08-10 US disclosed
US-4997844-A Compounds for the treatment of allergic or inflammatory diseases or shock conditions ICI AMERICAS INC. (US) 1991-03-05 US disclosed
EP-0179619-B1 HETEROCYCLIC AMIDES ICI AMERICAS INC. (US) 1990-09-05 EP disclosed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108482-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS MRGPRX4, MRGPRX1, MRGPRX2 LMNA 3618/4885TSHR 34/4885NR4A2 179/4885
US-20240300907-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS MRGPRX4, MRGPRX1, MRGPRX2 LMNA 3209/4885TSHR 98/4885NR4A2 344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.