Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 10/20 | 0.56 |
| ▸ | FNTB | P49356 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998378 | 0.79 | FNTA (0.68) | FNTAFNTBLMNASMN1; SMN2 | |
| SCHEMBL6176740 | 0.77 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL6991517 | 0.74 | MAP3K14 (0.44) | FNTAFNTB | |
| SCHEMBL6996211 | 0.73 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6995947 | 0.73 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7001749 | 0.72 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL7001745 | 0.72 | FNTA (0.64) | FNTAFNTB | |
| SCHEMBL8169075 | 0.71 | FNTA (0.75) | FNTAFNTB | |
| SCHEMBL7001329 | 0.69 | LMNA (0.54) | FNTAFNTBLMNASMN1; SMN2 | |
| SCHEMBL14289999 | 0.67 | FNTA (0.64) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |