Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112118 | 0.84 | ROCK1 (0.37) | DRD1ROCK1PRCPTRPM8KDM4E | |
| SCHEMBL6995922 | 0.81 | DRD1 (0.39) | DRD1LIPEPRCPTRPM8KDM4E | |
| SCHEMBL6992293 | 0.78 | GRIN1 (0.40) | DRD1LIPEPRCPGRIN2DGRIN3B | |
| SCHEMBL23112145 | 0.78 | TRPV1 (0.34) | ROCK1TRPV1 | |
| SCHEMBL6994963 | 0.76 | DRD1 (0.38) | DRD1LIPEPRCPGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL8805271 | 0.75 | PRCP (0.40) | DRD1LIPEPRCPTRPM8GRIN2D | |
| Hydrochloric Acid SCHEMBL8120961 | 0.74 | MKNK1 (0.49) | — | |
| SCHEMBL6957781 | 0.73 | DRD1 (0.39) | DRD1LIPEPRCPTRPM8GRM5 | |
| SCHEMBL7000740 | 0.73 | DRD1 (0.39) | DRD1LIPEPRCPTRPM8GRM5 | |
| SCHEMBL6995013 | 0.73 | DRD1 (0.39) | DRD1LIPEPRCPTRPM8GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |