Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992293 | 0.91 | GRIN1 (0.40) | DRD1HTR1APRCPLIPEGRIN1 | |
| SCHEMBL6995922 | 0.82 | DRD1 (0.39) | DRD1PRCPL3MBTL1LIPEGRIN1 | |
| Hydrochloric Acid SCHEMBL7001992 | 0.81 | PKM (0.33) | DRD1HTR1APKMPRCPL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7001990 | 0.79 | KMT2A (0.40) | HTR1APKM | |
| SCHEMBL6989353 | 0.79 | BLM (0.36) | — | |
| Hydrochloric Acid SCHEMBL6994782 | 0.78 | KCNH3 (0.37) | — | |
| SCHEMBL7000418 | 0.76 | GALR2 (0.35) | — | |
| SCHEMBL6994246 | 0.76 | DRD1 (0.40) | DRD1PRCPLIPEGRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL6993369 | 0.75 | GALR2 (0.35) | — | |
| SCHEMBL8572318 | 0.73 | DRD1 (0.40) | DRD1HTR1APRCPLIPEGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |