Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992293 | 0.84 | GRIN1 (0.40) | DRD1GRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL6994963 | 0.82 | DRD1 (0.38) | DRD1GRIN1GRIN2BLIPEL3MBTL1 | |
| SCHEMBL6994246 | 0.81 | DRD1 (0.40) | DRD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8572367 | 0.81 | DRD1 (0.40) | DRD1SPRGRIN2DGRIN3BCHRM1 | |
| Hydrochloric Acid SCHEMBL6997305 | 0.79 | SPR (0.35) | SPRGRIN2DGRIN3BCHRM1ADRA1D | |
| SCHEMBL6995426 | 0.78 | TAAR1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6997300 | 0.77 | KMT2A (0.40) | MAPTALDH1A1KMT2A | |
| SCHEMBL6995013 | 0.77 | DRD1 (0.39) | DRD1SPRLIPEAHRAKR1C3 | |
| SCHEMBL6957781 | 0.77 | DRD1 (0.39) | DRD1SPRLIPEAHRAKR1C3 | |
| SCHEMBL7000740 | 0.77 | DRD1 (0.39) | DRD1SPRLIPEAHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| US-5750531-A | ANTISECRETORY AGENTS FOR THE TREATMENT OF PEPTIC ULCER | YUHAN CORPORATION (KR) | 1998-05-12 | — | — | US | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |