Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998141 | 0.76 | GAA (0.49) | GAADDAH1PKMKRASPOLB | |
| SCHEMBL230024 | 0.75 | GAA (0.78) | GAADDAH1PKMKRASPOLB | |
| Iodomethane SCHEMBL27491515 | 0.73 | GAA (0.70) | GAADDAH1PKMKRASPOLB | |
| SCHEMBL6992236 | 0.72 | GAA (0.55) | GAADDAH1PKMKRASPOLB | |
| SCHEMBL6993752 | 0.70 | GAA (0.53) | GAADDAH1PKMKRASPOLB | |
| SCHEMBL9029321 | 0.70 | NPC1 (0.34) | GAADDAH1PKMKRASPOLB | |
| SCHEMBL11783603 | 0.69 | SMN1; SMN2 (0.50) | GAAPOLBLMNA | |
| SCHEMBL7000055 | 0.69 | GAA (0.51) | GAADDAH1PKMKRASPOLB | |
| Bendazol SCHEMBL29539948 | 0.69 | GAA (1.00) | GAADDAH1PKMKRASPOLB | |
| Bendazol SCHEMBL309393 | 0.69 | GAA (1.00) | GAADDAH1PKMKRASPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | claimed |
| EP-1189889-B1 | COMPOSITIONS AND METHODS FOR INHIBITING CELL DEATH | ELAN PHARMA INT LTD (IE) | 2003-12-17 | — | — | EP | disclosed |
| US-6541486-B1 | Used for treating ischemia, such as results from stroke or myocardial infarction, trauma, neurodegeneration, and inflammation. | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-01 | — | — | US | disclosed |