Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082572 | 0.71 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL22568074 | 0.68 | CA1 (0.38) | AKR1B1 | |
| SCHEMBL28363113 | 0.64 | AKR1B1 (0.37) | AKR1B1 | |
| SCHEMBL3678520 | 0.62 | ALDH1A1 (0.36) | AKR1B1 | |
| SCHEMBL16385968 | 0.61 | — | — | |
| SCHEMBL16093500 | 0.60 | ERN1 (0.40) | AKR1B1 | |
| SCHEMBL23917711 | 0.59 | ERN1 (0.42) | AKR1B1 | |
| SCHEMBL3677774 | 0.59 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL7959993 | 0.59 | CA1 (0.32) | AKR1B1 | |
| SCHEMBL4943759 | 0.58 | IMPDH2 (0.42) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931083-B1 | PROCESS FOR PRODUCING ECTEINASCIDIN COMPOUNDS | HARVARD COLLEGE (US) | 2003-02-19 | — | — | EP | claimed |
| US-5721362-A | Process for producing ecteinascidin compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1998-02-24 | — | — | US | claimed |
| EP-0931083-B1 | PROCESS FOR PRODUCING ECTEINASCIDIN COMPOUNDS | HARVARD COLLEGE (US) | 2003-02-19 | — | — | EP | disclosed |
| US-5721362-A | Process for producing ecteinascidin compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1998-02-24 | — | — | US | disclosed |