SCHEMBL6994962

SCHEMBL6994962

NC(CF)(CF)C(=O)CC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6995020 0.72 KDM4E (0.31)
SCHEMBL2892041 0.69 FAAH (0.40)
SCHEMBL5653486 0.67
Hydrochloric Acid SCHEMBL4666352 0.65 KDM4E (0.31)
SCHEMBL14769297 0.65 LIPA (0.36)
Hydrochloric Acid SCHEMBL28104635 0.65 ODC1 (0.60) ODC1
SCHEMBL8406316 0.65 KMT2A (0.33)
SCHEMBL2000632 0.65 CES1 (0.30)
SCHEMBL211941 0.64
SCHEMBL4486281 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0931082-B1 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 2003-03-19 EP disclosed
US-6221894-B1 ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS. MERCK & CO., INC. 2001-04-24 US disclosed
EP-0931082-A4 NODULISPORIC ACID DERIVATIVES MERCK & CO INC (US) 1999-11-17 EP disclosed
US-5962499-A ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS MERCK & CO., INC. (US) 1999-10-05 US disclosed
EP-0931082-A1 NODULISPORIC ACID DERIVATIVES Merck & Co., Inc. (a New Jersey corp.) (US) 1999-07-28 EP disclosed
WO-1998012196-A1 NODULISPORIC ACID DERIVATIVES MERCK & CO., INC. (US) 1998-03-26 WO disclosed