Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653486 | 0.78 | — | — | |
| SCHEMBL22664246 | 0.78 | KDM4E (0.33) | KDM4EHMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL8406316 | 0.78 | KMT2A (0.33) | HMGCRCHRM1TBXA2RADRA1AFAAH | |
| Hydrochloric Acid SCHEMBL4666352 | 0.77 | KDM4E (0.31) | KDM4E | |
| SCHEMBL6996717 | 0.75 | FAAH (0.32) | FAAH | |
| SCHEMBL6994962 | 0.72 | ODC1 (0.39) | — | |
| SCHEMBL18291779 | 0.72 | PLA2G4A (0.34) | FAAH | |
| SCHEMBL5491344 | 0.72 | HMGCR (0.35) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL2892041 | 0.71 | FAAH (0.40) | FAAH | |
| SCHEMBL8306696 | 0.70 | FAAH (0.32) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931082-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 1999-11-17 | — | — | EP | claimed |
| EP-0931082-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (a New Jersey corp.) (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1998012196-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1998-03-26 | — | — | WO | claimed |
| EP-0931082-B1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6221894-B1 | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS. | MERCK & CO., INC. | 2001-04-24 | — | — | US | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |