Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995341 | 1.00 | ACHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL6995337 | 1.00 | ACHE (0.48) | ACHEBACE1BCHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL6994544 | 0.93 | SLC6A12 (0.45) | ACHEBACE1BCHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL6994539 | 0.93 | SLC6A12 (0.45) | ACHEBACE1BCHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL6994531 | 0.93 | SLC6A12 (0.45) | ACHEBACE1BCHEMEN1KMT2A | |
| Fumaric Acid SCHEMBL6994532 | 0.93 | SLC6A12 (0.45) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL6999335 | 0.91 | HTR1A (0.43) | SIGMAR1 | |
| SCHEMBL6999326 | 0.91 | HTR1A (0.43) | SIGMAR1 | |
| SCHEMBL6999331 | 0.91 | HTR1A (0.43) | SIGMAR1 | |
| SCHEMBL6998399 | 0.89 | ABCB1 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | claimed |
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |