SCHEMBL6995706

SCHEMBL6995706

CN(C)S(=O)(=O)c1ccc(NC=C2C=NNC2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.52
▸ KMT2A Q03164 3/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MEN1 O00255 1/20 0.39
▸ ALDH1A1 P00352 4/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ HTT P42858 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ ABCC9 O60706 1/20 0.35
▸ ABCC8 Q09428 1/20 0.35
▸ KCNJ11 Q14654 1/20 0.35
▸ KCNJ8 Q15842 1/20 0.35
▸ NAMPT P43490 1/20 0.35
▸ TRPV4 Q9HBA0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7547189 1.00 LMNA (0.52) LMNAKMT2AKDM4EMEN1ALDH1A1
SCHEMBL7552469 0.74 MAPT (0.40) LMNAKMT2AKDM4EMEN1ALDH1A1
SCHEMBL7549680 0.66 ALDH1A1 (0.52) KMT2AMEN1ALDH1A1SMN1; SMN2NPC1
SCHEMBL13110655 0.64 LMNA (0.63) LMNAKMT2AKDM4EMEN1ALDH1A1
SCHEMBL7258699 0.63 LMNA (0.61) LMNAKMT2AKDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL14919180 0.62 LMNA (0.59) LMNAKMT2AKDM4EMEN1ALDH1A1
SCHEMBL13993978 0.60 LMNA (0.58) LMNAKMT2AKDM4EMEN1ALDH1A1
SCHEMBL7549357 0.60 CA1 (0.37) LMNAKMT2AMEN1ALDH1A1MAPK1
SCHEMBL21244024 0.60 LMNA (0.59) LMNAKMT2AKDM4EALDH1A1SMN1; SMN2
SCHEMBL116525 0.60 LMNA (0.59) LMNAKMT2AKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301787-A2 METHOD FOR DETECTING URACIL BIOSYNTHESIS INHIBITORS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-04-16 — — EP claimed
US-20020058244-A1 Method for detecting uracil biosynthesis inhibitors and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 2002-05-16 — — US claimed
WO-2002006512-A2 METHOD FOR DETECTING URACIL BIOSYNTHESIS INHIBITORS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2002-01-24 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058244-A1 Method for detecting uracil biosynthesis inhibitors and their use as herbicides UMPS, UGP2, UNG LMNA 4693/4885KMT2A 2193/4885KDM4E 1474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback