Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6992777 | 0.99 | CHRM2 (0.40) | CHRM2PARP1MAPTMEN1KMT2A | |
| SCHEMBL6991287 | 0.90 | KMT2A (0.44) | PARP1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL6997432 | 0.89 | KMT2A (0.44) | PARP1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7000763 | 0.83 | PARP1 (0.43) | CHRM2PARP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6999676 | 0.83 | PARP1 (0.43) | PARP1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7000628 | 0.83 | PARP1 (0.41) | PARP1KMT2ACA12CA1CA2 | |
| SCHEMBL6999572 | 0.83 | CA1 (0.46) | PARP1MEN1KMT2ACA12CA1 | |
| SCHEMBL7001786 | 0.83 | TDP1 (0.46) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL6994032 | 0.82 | LMNA (0.42) | CHRM2PARP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7713373 | 0.82 | PARP1 (0.53) | PARP1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |