Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 6/20 | 0.39 |
| ▸ | DRD5 | P21918 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995776 | 1.00 | HTR1A (0.44) | HTR1ASMN1; SMN2DRD2HTR2AHTR7 | |
| Oxalic Acid SCHEMBL6994123 | 0.94 | MEN1 (0.43) | HTR1ACYP2D6CYP2C19MEN1KMT2A | |
| Oxalic Acid SCHEMBL6996118 | 0.94 | MEN1 (0.43) | HTR1ACYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL6991324 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6991320 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6993677 | 0.83 | HRH1 (0.51) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL6993882 | 0.83 | HRH1 (0.51) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8561183 | 0.83 | HRH1 (0.51) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL6993670 | 0.83 | HRH1 (0.51) | DRD2DRD1DRD4DRD5DRD3 | |
| Oxalic Acid SCHEMBL6991632 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | claimed |
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |