Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 10/20 | 0.51 |
| ▸ | DRD1 | P21728 | 6/20 | 0.51 |
| ▸ | DRD5 | P21918 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993670 | 1.00 | HRH1 (0.51) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL6993882 | 1.00 | HRH1 (0.51) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL8561183 | 1.00 | HRH1 (0.51) | HRH1DRD1DRD5DRD4DRD3 | |
| Oxalic Acid SCHEMBL6992364 | 0.95 | KDM4E (0.48) | HRH1DRD1DRD5DRD4DRD3 | |
| Oxalic Acid SCHEMBL6998099 | 0.95 | KDM4E (0.48) | HRH1DRD1DRD5DRD4DRD3 | |
| Oxalic Acid SCHEMBL6992367 | 0.95 | KDM4E (0.48) | HRH1DRD1DRD5DRD4DRD3 | |
| SCHEMBL6991324 | 0.85 | ALDH1A1 (0.52) | L3MBTL1TP53MEN1KMT2AKDM4E | |
| SCHEMBL6991320 | 0.85 | ALDH1A1 (0.52) | L3MBTL1TP53MEN1KMT2AKDM4E | |
| SCHEMBL6995776 | 0.83 | HTR1A (0.44) | DRD1DRD5DRD4DRD3DRD2 | |
| SCHEMBL6995780 | 0.83 | HTR1A (0.44) | DRD1DRD5DRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | claimed |
| EP-0853615-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1998-07-22 | — | — | EP | claimed |
| WO-1997010212-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-03-20 | — | — | WO | claimed |
| EP-0853615-B1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH AS (DK) | 2003-12-10 | — | — | EP | disclosed |