Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994746 | 0.81 | TAS1R3 (0.52) | TAS1R3TAS1R1MAOBMAPTCASP3 | |
| SCHEMBL648621 | 0.81 | MAOB (0.70) | TAS1R3TAS1R1MAOBMAPTCASP3 | |
| SCHEMBL12795529 | 0.78 | TAS1R3 (0.58) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL446971 | 0.78 | TAS1R3 (0.64) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL5806063 | 0.75 | TAS1R3 (0.60) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL6998647 | 0.75 | CLK1 (0.53) | — | |
| SCHEMBL31060243 | 0.74 | FLT3 (0.71) | TAS1R3TAS1R1MAPTCASP3SENP7 | |
| SCHEMBL24522315 | 0.74 | TAS1R3 (0.73) | TAS1R3TAS1R1HDAC3HDAC4HDAC1 | |
| SCHEMBL12848552 | 0.74 | TAS1R3 (0.65) | TAS1R3TAS1R1MAOBHDAC3HDAC4 | |
| SCHEMBL29362997 | 0.74 | TAS1R3 (0.73) | TAS1R3TAS1R1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943618-B1 | 1,2-dioxetane derivative | MATSUMOTO MASAKATSU (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6218135-B1 | EASY TO HANDLE, HEAT STABLE, AND HIGH IN EMISSION EFFICIENCY; FOR IMMUNOASSAYS | Matsumoto, Masakatsu (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0943618-A2 | 1,2-dioxetane derivative | FUJIREBIO INC. (JP) | 1999-09-22 | — | — | EP | disclosed |