Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 8/20 | 0.32 |
| ▸ | DRD2 | P14416 | 6/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144008 | 0.95 | DRD3 (0.33) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL6621027 | 0.89 | DRD3 (0.34) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL6994951 | 0.85 | PTPN1 (0.36) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL6774144 | 0.85 | DRD3 (0.36) | DRD3DRD2DRD4DRD1GRM5 | |
| SCHEMBL6997801 | 0.85 | DRD3 (0.32) | KDM4EALDH1A1HPGDDRD3DRD2 | |
| SCHEMBL6997471 | 0.83 | KDM4E (0.31) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL6997468 | 0.83 | KDM4E (0.31) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL6773167 | 0.80 | GRM5 (0.35) | KDM4EMEN1MAPTKMT2ARECQL | |
| SCHEMBL9040855 | 0.80 | PTPN1 (0.39) | KDM4EMAPTALDH1A1HPGDDRD3 | |
| SCHEMBL7000263 | 0.80 | MDM2 (0.39) | KMT2AL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557526-B1 | PYRROLOAZEPINE COMPOUND | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5399557-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0557526-A1 | PYRROLOAZEPINE COMPOUND | SUNTORY LIMITED (JP) | 1993-09-01 | — | — | EP | disclosed |