Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773167 | 0.92 | GRM5 (0.35) | PTPN1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9040855 | 0.86 | PTPN1 (0.39) | PTPN1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9040322 | 0.86 | PTPN1 (0.35) | PTPN1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL6996046 | 0.85 | KDM4E (0.33) | PTPN1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9041335 | 0.85 | PTPN1 (0.37) | PTPN1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL6993447 | 0.84 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL6993449 | 0.84 | ALDH1A1 (0.32) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL7000263 | 0.84 | MDM2 (0.39) | PTPN1KMT2AL3MBTL1 | |
| SCHEMBL7144008 | 0.81 | DRD3 (0.33) | PTPN1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9041444 | 0.80 | PTPN1 (0.35) | PTPN1MEN1KMT2APOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557526-B1 | PYRROLOAZEPINE COMPOUND | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5399557-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0557526-A1 | PYRROLOAZEPINE COMPOUND | SUNTORY LIMITED (JP) | 1993-09-01 | — | — | EP | disclosed |