Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774193 | 0.93 | ACHE (0.40) | MDM2KMT2ACTDSP1PTPN1ACHE | |
| SCHEMBL9041354 | 0.87 | L3MBTL1 (0.39) | MDM2KMT2ACTDSP1DDB1CRBN | |
| SCHEMBL6994951 | 0.84 | PTPN1 (0.36) | KMT2APTPN1L3MBTL1 | |
| SCHEMBL6993124 | 0.84 | HTR1A (0.49) | — | |
| SCHEMBL6991433 | 0.80 | L3MBTL1 (0.39) | MDM2KMT2ACTDSP1DDB1CRBN | |
| SCHEMBL6996046 | 0.80 | KDM4E (0.33) | KMT2APTPN1L3MBTL1 | |
| SCHEMBL6989705 | 0.80 | L3MBTL1 (0.41) | MDM2KMT2ACTDSP1ACHEDDB1 | |
| SCHEMBL6988025 | 0.79 | L3MBTL1 (0.39) | MDM2KMT2ACTDSP1DDB1CRBN | |
| SCHEMBL9040855 | 0.79 | PTPN1 (0.39) | PTPN1 | |
| SCHEMBL6987269 | 0.78 | L3MBTL1 (0.38) | MDM2KMT2ACTDSP1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557526-B1 | PYRROLOAZEPINE COMPOUND | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5399557-A | Cardiovascular disorders | SUNTORY LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0557526-A1 | PYRROLOAZEPINE COMPOUND | SUNTORY LIMITED (JP) | 1993-09-01 | — | — | EP | disclosed |