Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996056 | 0.83 | KCNN4 (0.30) | KCNN4 | |
| Hydrochloric Acid SCHEMBL6994220 | 0.79 | MEN1 (0.43) | — | |
| SCHEMBL7462849 | 0.78 | GSK3A (0.50) | F2 | |
| Hydrochloric Acid SCHEMBL6995781 | 0.77 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL6998534 | 0.77 | GSK3A (0.49) | F2 | |
| Hydrochloric Acid SCHEMBL6995488 | 0.74 | GSK3A (0.49) | — | |
| Hydrochloric Acid SCHEMBL6994528 | 0.74 | NPSR1 (0.53) | F2 | |
| Hydrochloric Acid SCHEMBL6990392 | 0.73 | NPSR1 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL6989334 | 0.70 | NOS3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6989457 | 0.70 | PAX8 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927177-B1 | NOVEL BENZOTHIOPHENE DERIVATIVES, THEIR PREPARATION AND USE AS UROKINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-11-26 | — | — | EP | disclosed |
| US-6274619-B1 | FUSED AMIDINO TYPE COMPOUNDS SUCH AS 4-(N-BUTYLCARBAMOYLMETHYLIDENE)-2-AMIDINO-4,5,6,7-TETRAHYDROBE NZO(B)THIOPHENE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-14 | — | — | US | disclosed |
| US-6093710-A | AN ENZYME INHIBITOR TREATING ANGIOGENESIS, ARTHRITIS, INFLAMMATION, METASTASIS, OSTEOPOROSIS, TUMORSANGIOGENESIS-DEPENDENT RETINOPATHIES, CONTRACEPTIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-25 | — | — | US | disclosed |