Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 16/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520406 | 0.86 | SIGMAR1 (0.50) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL8775838 | 0.84 | TBXAS1 (0.75) | TBXAS1TBXA2R | |
| SCHEMBL8775831 | 0.84 | TBXAS1 (0.75) | TBXAS1TBXA2R | |
| SCHEMBL10471121 | 0.81 | TBXAS1 (0.76) | TBXAS1TBXA2R | |
| SCHEMBL7690245 | 0.81 | TBXAS1 (0.76) | TBXAS1TBXA2R | |
| SCHEMBL8418666 | 0.81 | TBXAS1 (0.54) | SIGMAR1TBXAS1 | |
| SCHEMBL1807584 | 0.81 | TBXAS1 (0.54) | SIGMAR1TBXAS1TBXA2R | |
| SCHEMBL11229130 | 0.81 | TBXAS1 (0.54) | SIGMAR1TBXAS1 | |
| SCHEMBL11792681 | 0.81 | TBXAS1 (0.54) | SIGMAR1TBXAS1 | |
| SCHEMBL7861116 | 0.81 | TBXAS1 (0.54) | SIGMAR1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |