Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999571 | 0.85 | — | — | |
| SCHEMBL6998349 | 0.84 | KCNH2 (0.34) | — | |
| SCHEMBL8133148 | 0.83 | — | — | |
| SCHEMBL6999701 | 0.82 | MEN1 (0.30) | — | |
| SCHEMBL6997540 | 0.81 | SMYD3 (0.38) | — | |
| SCHEMBL7711553 | 0.76 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL8137237 | 0.76 | ALOX5 (0.35) | — | |
| SCHEMBL6995697 | 0.75 | ALOX5 (0.31) | — | |
| SCHEMBL6994308 | 0.74 | CYP3A4 (0.32) | CYP2C19 | |
| SCHEMBL6993302 | 0.74 | ALOX5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | disclosed |
| EP-1015437-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012915-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |