Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994266 | 0.84 | KMT2A (0.53) | ALDH1A1KDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL14456693 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL5339147 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL5342007 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL6995476 | 0.75 | L3MBTL1 (0.67) | ALDH1A1KDM4EKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL2595538 | 0.74 | HSD17B10 (0.48) | ALDH1A1KMT2ASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL2595536 | 0.74 | HSD17B10 (0.48) | ALDH1A1KMT2ASMN1; SMN2GAAHSD17B10 | |
| SCHEMBL8909931 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL14107969 | 0.73 | KMT2A (0.54) | ALDH1A1KMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL24109309 | 0.73 | KMT2A (0.65) | ALDH1A1KMT2ASMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |