Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 9/20 | 0.35 |
| ▸ | CA2 | P00918 | 9/20 | 0.35 |
| ▸ | CA9 | Q16790 | 9/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 8/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468785 | 0.80 | MYC (0.39) | CYP3A4MAPTCASP1SMN1; SMN2TSHR | |
| SCHEMBL696837 | 0.77 | ALDH1A1 (0.35) | MAPTBLMSMN1; SMN2TSHRKDM4E | |
| SCHEMBL28672147 | 0.71 | GPBAR1 (0.45) | TP53MAOAMAOBTDP1 | |
| SCHEMBL25488361 | 0.71 | CA12 (0.42) | TP53MAPTSMN1; SMN2CA12CA2 | |
| SCHEMBL692668 | 0.71 | CA12 (0.31) | CA12CA2CA9CA1 | |
| SCHEMBL2563881 | 0.70 | TDP1 (0.46) | TP53CA12CA2CA9CA1 | |
| SCHEMBL692944 | 0.68 | LMNA (0.40) | MAPTLMNA | |
| SCHEMBL8847131 | 0.67 | NAPRT (0.48) | CA12CA2CA9CA1CA14 | |
| SCHEMBL692424 | 0.67 | ADORA2B (0.40) | MAPTBLMSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL19939976 | 0.67 | NAPRT (0.44) | TP53CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| EP-2421613-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123866-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND A CHELANT AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |