Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 6/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201523 | 0.77 | ENPP3 (0.96) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL7148308 | 0.76 | AOC3 (0.48) | ENPP3ENPP1 | |
| SCHEMBL8117354 | 0.73 | ENPP3 (0.69) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL19626581 | 0.73 | ENPP3 (0.66) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL6326200 | 0.73 | ENPP3 (0.60) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL12112408 | 0.73 | ENPP3 (0.96) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL2056108 | 0.72 | TP53 (0.69) | ENPP3ENPP1TP53POLBTHRB | |
| Ammonia Solution, Strong SCHEMBL28862464 | 0.71 | ENPP3 (0.92) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL24415640 | 0.70 | ENPP3 (0.69) | ENPP3ENPP1TP53POLBTHRB | |
| SCHEMBL2056109 | 0.70 | ENPP3 (0.69) | ENPP3ENPP1TP53POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326861-A1 | ALPHA-ARYL ETHANOLAMINES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | Pfizer Products Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032897-A1 | ALPHA-ARYL ETHANOLAMINES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2002-04-25 | — | — | WO | disclosed |