Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanate SCHEMBL8557386 | 0.91 | CTSD (0.43) | CTSDHPGDALDH1A1STAT3NPC1 | |
| SCHEMBL8557389 | 0.89 | CTSD (0.42) | CTSDHPGDALDH1A1STAT3NPC1 | |
| SCHEMBL28358167 | 0.85 | CA12 (0.41) | CTSDHTTKCNK3KCNK9 | |
| SCHEMBL5824394 | 0.84 | CTSD (0.49) | CTSDHPGDALDH1A1STAT3NPC1 | |
| SCHEMBL1043130 | 0.83 | PTGS2 (0.59) | HPGDALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL6276558 | 0.81 | ABCG2 (0.46) | CTSDHPGDALDH1A1STAT3NPC1 | |
| SCHEMBL9731758 | 0.81 | IRAK4 (0.58) | HPGDALDH1A1KCNK3KCNK9HSD17B10 | |
| SCHEMBL9731442 | 0.81 | HCRTR1 (0.54) | HPGDALDH1A1RAB9AHTTKCNK3 | |
| SCHEMBL3395153 | 0.80 | ALDH1A1 (0.42) | HPGDALDH1A1NPC1SMN1; SMN2GAA | |
| SCHEMBL11006546 | 0.80 | CA12 (0.55) | HPGDALDH1A1SMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0497367-B1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5221685-A | Insecticides, miticides or fungicides | UBE INDUSTRIES, LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0497367-A1 | Thiazoline derivatives, processes for their preparation and pesticidal compositions containing them | UBE INDUSTRIES, LTD. (JP) | 1992-08-05 | — | — | EP | disclosed |
| US-5106843-A | Treatment of migraine, emesis, anxiety, gastrointestinal disorders, psychological disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0323077-B1 | HETEROCYCLIC COMPOUNDS | JOHN WYETH & BROTHER LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4983600-A | Antiemetics, antianxiety agents, gastrointestinal disorders | JOHN WYETH & BROTHER LIMITED (GB) | 1991-01-08 | — | — | US | disclosed |
| EP-0323077-A1 | Heterocyclic compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1989-07-05 | — | — | EP | disclosed |