Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6995114 | 0.99 | MEN1 (0.39) | MEN1KMT2APARP1HTTALDH1A1 | |
| SCHEMBL7002617 | 0.84 | PARP1 (0.41) | MEN1KMT2APARP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6998857 | 0.83 | MEN1 (0.44) | MEN1KMT2APARP1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6995038 | 0.83 | PARP1 (0.40) | MEN1KMT2APARP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7713373 | 0.82 | PARP1 (0.53) | MEN1KMT2APARP1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6310054 | 0.82 | PARP1 (0.42) | MEN1KMT2APARP1 | |
| SCHEMBL7002250 | 0.81 | PARP1 (0.42) | PARP1MAPK1L3MBTL1 | |
| SCHEMBL7002470 | 0.81 | PARP1 (0.42) | PARP1 | |
| Hydrochloric Acid SCHEMBL7000763 | 0.81 | PARP1 (0.43) | MEN1KMT2APARP1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6999676 | 0.81 | PARP1 (0.43) | MEN1KMT2APARP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |