Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6995038 | 0.99 | PARP1 (0.40) | PARP1PDGFRBKDRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8133176 | 0.95 | PARP1 (0.40) | PARP1PDGFRBKDRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6998857 | 0.85 | MEN1 (0.44) | PARP1MEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL6994032 | 0.84 | LMNA (0.42) | PARP1PDGFRBKDRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7713373 | 0.84 | PARP1 (0.53) | PARP1PDGFRBKDRMEN1KMT2A | |
| SCHEMBL6997265 | 0.84 | MEN1 (0.40) | PARP1MEN1KMT2ACA1CA2 | |
| SCHEMBL7002250 | 0.84 | PARP1 (0.42) | PARP1PDGFRBKDRMAPK1SCN8A | |
| Hydrochloric Acid SCHEMBL6996205 | 0.83 | PARP1 (0.41) | PARP1PDGFRBKDRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6995114 | 0.83 | MEN1 (0.39) | PARP1MEN1KMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL7001196 | 0.83 | PARP1 (0.41) | PARP1PDGFRBKDRSCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AG (DE) | 2003-12-03 | — | — | EP | claimed |