Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6993593 | 0.99 | GRIN2D (0.44) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL6998551 | 0.85 | GRIN2D (0.43) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL6994942 | 0.84 | GRIN2D (0.43) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL7001354 | 0.81 | CCNA2 (0.51) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL6989818 | 0.80 | CCNA2 (0.50) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL7821547 | 0.80 | LMNA (0.65) | LMNAHTTSMN1; SMN2GAATP53 | |
| SCHEMBL6997622 | 0.80 | MEN1 (0.45) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL7822581 | 0.79 | LMNA (0.67) | LMNAHTTSMN1; SMN2GAATP53 | |
| Hydrochloric Acid SCHEMBL6997347 | 0.79 | KDM4E (0.45) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A | |
| SCHEMBL6990874 | 0.77 | MEN1 (0.42) | GRIN2DGRIN3BCHRM1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | claimed |
| CN-1102144-C | Noval pyrimidine derivatives and prepn. processes thereof | YUHAN CORP (KR) | 2003-02-26 | — | — | CN | disclosed |