Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | PDE5A | O76074 | 8/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987648 | 0.86 | PDE2A (0.47) | KDM4EPDE2A | |
| SCHEMBL6996492 | 0.79 | PDE2A (0.47) | PDE2A | |
| SCHEMBL4947310 | 0.78 | PDE2A (0.62) | PDE2A | |
| SCHEMBL6998591 | 0.77 | PDE2A (0.45) | KDM4EPDE2A | |
| SCHEMBL6991547 | 0.76 | PDE2A (0.49) | KDM4EPDE2AADORA3 | |
| SCHEMBL6997188 | 0.76 | CCNE2 (0.52) | KDM4EPDE2A | |
| SCHEMBL6987730 | 0.74 | GAA (0.43) | KDM4EPDE2A | |
| SCHEMBL6993084 | 0.73 | PDE9A (0.46) | PDE2A | |
| SCHEMBL6997368 | 0.72 | CCNE2 (0.51) | PDE2A | |
| SCHEMBL18283043 | 0.71 | KMT2A (0.40) | KDM4EPDE2APDE5AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973774-B1 | 1,5-DIHYDRO-PYRAZOLO 3,4-D]-PYRIMIDINONE DERIVATIVES | BAYER AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6174884-B1 | CARDIOVASCULAR DISORDERS; CEREBROVASCULAR DISEASES; VASCULAR SYSTEM DISORDERS, ESPECIALLY THE PERIPHERAL BLOOD VESSELS; UROGENITAL DISORDERS; HYPOTENSIVE AGENTS; ANTIARRYTHMIA AND -ISCHEMIC AGENTS; PHOSPHODIESTERASE ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-16 | — | — | US | disclosed |