Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000043 | 0.87 | DRD2 (0.46) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| SCHEMBL6993800 | 0.85 | DRD2 (0.47) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| SCHEMBL6997100 | 0.84 | DRD2 (0.65) | DRD2HTR2AHTR1AHTR6 | |
| SCHEMBL6993415 | 0.74 | HTR2A (0.52) | DRD2HTR2AHTR6HTR2C | |
| SCHEMBL6997109 | 0.72 | DRD2 (0.46) | DRD2HTR2AHTR1AHTR6 | |
| SCHEMBL6186847 | 0.72 | HTR1D (0.54) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| SCHEMBL1545312 | 0.71 | HTR1D (0.50) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| SCHEMBL9117307 | 0.71 | HTR1D (0.50) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL1545002 | 0.71 | HTR1D (0.49) | DRD2HTR1DHTR1BHTR2AHTR1A | |
| SCHEMBL7001825 | 0.70 | DRD2 (0.65) | DRD2HTR2AHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915881-B1 | PYRROLOAZEPINE COMPOUNDS | SUNTORY LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6211362-B1 | CHEMICAL INTERMEDIATE FOR DRUGS | SUNTORY LIMITED (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6187772-B1 | Pyrroloazepine compounds | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |