Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998054 | 1.00 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL6998063 | 1.00 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL6999111 | 0.88 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL6999106 | 0.88 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL6996305 | 0.87 | DRD1 (0.40) | L3MBTL1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6997554 | 0.87 | DRD1 (0.40) | L3MBTL1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6996299 | 0.87 | DRD1 (0.40) | L3MBTL1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6994077 | 0.85 | DRD1 (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL6994080 | 0.85 | DRD1 (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL6994627 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |