Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994623 | 1.00 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1CHRM2HTR1A | |
| SCHEMBL6994619 | 1.00 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL7093323 | 0.99 | ALDH1A1 (0.45) | ALDH1A1POLBMEN1CHRM2HTR1A | |
| SCHEMBL6998050 | 0.82 | L3MBTL1 (0.37) | ALDH1A1MEN1DRD3KMT2AHTR2A | |
| SCHEMBL6998054 | 0.82 | L3MBTL1 (0.37) | ALDH1A1MEN1DRD3KMT2AHTR2A | |
| SCHEMBL6998063 | 0.82 | L3MBTL1 (0.37) | ALDH1A1MEN1DRD3KMT2AHTR2A | |
| SCHEMBL1597990 | 0.81 | HTR1A (0.43) | ALDH1A1HTR1AADRA1ADRD3DRD2 | |
| SCHEMBL7094412 | 0.81 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1CHRM2HTR1A | |
| SCHEMBL6996299 | 0.81 | DRD1 (0.40) | DRD1KMT2A | |
| SCHEMBL6997554 | 0.81 | DRD1 (0.40) | DRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | claimed |