Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982789 | 0.92 | PTPN1 (0.35) | PTPN1POLBRECQLADORA2B | |
| SCHEMBL9041754 | 0.91 | PTPN1 (0.34) | PTPN1POLBRECQLADORA2B | |
| SCHEMBL9041444 | 0.88 | PTPN1 (0.35) | PTPN1POLBRECQLADORA2BMEN1 | |
| SCHEMBL6993141 | 0.86 | MEN1 (0.32) | POLBRECQLMEN1KMT2A | |
| SCHEMBL7948427 | 0.84 | AOC3 (0.30) | POLBRECQL | |
| SCHEMBL7948424 | 0.84 | AOC3 (0.30) | POLBRECQL | |
| SCHEMBL9040322 | 0.81 | PTPN1 (0.35) | PTPN1POLBADORA2BMEN1KMT2A | |
| SCHEMBL9040778 | 0.81 | PTPN1 (0.33) | PTPN1ADORA2B | |
| SCHEMBL9041335 | 0.80 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL6989876 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915881-B1 | PYRROLOAZEPINE COMPOUNDS | SUNTORY LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6211362-B1 | CHEMICAL INTERMEDIATE FOR DRUGS | SUNTORY LIMITED (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6187772-B1 | Pyrroloazepine compounds | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |