Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994882 | 0.92 | PTPN1 (0.31) | PNMT | |
| SCHEMBL6989751 | 0.91 | PNMT (0.32) | PNMT | |
| SCHEMBL6998066 | 0.86 | PTPN1 (0.33) | MEN1KMT2APOLBRECQL | |
| SCHEMBL9038657 | 0.79 | — | — | |
| SCHEMBL6992914 | 0.78 | HTR1A (0.53) | — | |
| SCHEMBL6982789 | 0.78 | PTPN1 (0.35) | POLBRECQL | |
| SCHEMBL9041754 | 0.77 | PTPN1 (0.34) | POLBRECQL | |
| SCHEMBL9041444 | 0.77 | PTPN1 (0.35) | MEN1KMT2APOLBRECQL | |
| SCHEMBL6996176 | 0.74 | DRD2 (0.59) | — | |
| SCHEMBL6995885 | 0.74 | DRD2 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915881-B1 | PYRROLOAZEPINE COMPOUNDS | SUNTORY LTD (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6211362-B1 | CHEMICAL INTERMEDIATE FOR DRUGS | SUNTORY LIMITED (JP) | 2001-04-03 | — | — | US | disclosed |
| US-6187772-B1 | Pyrroloazepine compounds | SUNTORY LIMITED (JP) | 2001-02-13 | — | — | US | disclosed |